First and foremost: Sleep in total darkness, your brain does not go into a sleep mode if there is any light around you.

An adequate and restful sleep provides the chance for the brain to recuperate, repair and revitalize.

Our Brain cells produce different Neurotransmitters. One of which is GABA - Gamma Amino Butyric Acid.  GABAergic mechanisms have been found in various organs in the body, such as the lungs, liver, stomach, intestine, pancreas, uterus, fallopian tubes, ovaries, testicles, kidneys and bladder.

GABA has a relaxing, anti-anxiety and anticonvulsive effect. GABA is also responsible for the regulation of muscle tone and regulates the growth of embryonic and neuronal stem cells. Alcoholic drinks produce their relaxing effect through GABA receptor stimulation.

Natural treatments and supplements have been used for sleep disorders, stress relief and for brain disorders, such as anxiety and depression historically over thousands of years to promote healthy sleep, to reduce anxiety, and help with the emotional and physical effects of stress.

Melatonin is a naturally occurring compound found in animals and plants. Circulating levels of melatonin will vary in a daily cycle, allowing the circadian rhythms and therefore, several biological functions. 

Many biological effects of melatonin are produced through activation of melatonin receptors, while others are due to its role as a pervasive and powerful antioxidant, with a particular role in the protection of nuclear and mitochondrial DNA. Melatonin, in addition to promoting sleep, is involved in the immune response.

Recent studies on mice with Huntington's disease has shown that melatonin receptors were depleted on the mitochondria in the brain tissue. These findings have been detected in the brain tissue derived from humans affected with the disease as well. Reduction in the brain tissue has been found in other neurological disorders such as Alzheimer"s and parkinson's diseseases.

In human brain, melatonin is made from the essential dietary amino acid tryptophan, with serotonin produced at the second step. Melatonin is secreted into the blood by the pineal gland. Known as the "hormone of darkness," it is secreted in darkness in both day-active (diurnal) and night-active (nocturnal) animals.

Melatonin may also be produced by a variety of peripheral cells such as bone marrow cells, lymphocytes, and epithelial cells. Usually, the melatonin concentration in these cells is much higher than that found in the blood, but it does not seem to be regulated by the photoperiod.

Research has shown that when bird chicks ingest melatonin-rich plant feed, such as rice, the melatonin binds to melatonin receptors in their brains. No food has been found to elevate plasma melatonin levels in humans and therefore a supplement with melatonin would help.

Serving size:  2 Capsules

Each bottle contains: 60 capsules

Directions: Take one or two capsules before bedtime.