Our Brain cells produce different Neurotransmitters. Neurons that produce GABA - Gamma Amino Butiric Acid are called GABAergic neurons, and develop an inhibitory action as the brain matures into adulthood.  GABAergic mechanisms have been found in various organs in the body, such as the lungs, liver, stomach, intestine, pancreas, uterus, fallopian tubes, ovaries, testicles, kidneys and bladder. GABA has a relaxing, anti-anxiety and anticonvulsive effect. GABA is also responsible for the regulation of muscle tone and regulates the growth of embryonic and neuronal stem cells. Alcoholic drinks produce their relaxing effect through GABA receptor stimulation.

 Natural treatments and supplements have been used for sleep disorders, stress relief and for brain disorders, such as anxiety and depression historically over thousands of years by alternative medicine practitioners to promote healthy sleep, to reduce anxiety, and help with the emotional and physical effects of stress.

Kava Kava or Piper methysticum root extract is thought to work by enhancing the production of GABA in the brain.  
Research currently suggests that Kava does not alter levels of dopamine and serotonin in the Central nervous System.